List of software/websites/databases/other stuff for genome engineering
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Updated
Jul 29, 2026
List of software/websites/databases/other stuff for genome engineering
Software pipeline for the analysis of CRISPR-Cas9 genome editing outcomes from sequencing data
CRISPR/Cas-directed HDR genome editing suite: finds+scores gRNA targets, generates donor DNAs, & produces optimal cPCR primer designs.
Automatically create CRISPR guides for DASH ✂️
A large scale off-target analysis tool for CRISPR/Cas9 genome editing system
Annotates CRISPR–Cas repair outcomes from CRISPResso2 allele tables: cut geometry (blunt vs staggered), deletion orientation and size, microhomology context, and which DNA end participates in repair — with publication-ready charts and statistics.
Per-residue prediction of where SpCas9 tolerates an inserted protein domain, with calibrated probabilities and uncertainty (BART).
Conservation-constrained, escape-aware CRISPR guide design for HSV-1. Finds that the sampling resolution of the public genome corpus, not repair biology, limits how low an escape probability can be demonstrated.
Local CRISPR-Cas9 guide off-target scanner. Core PAM scan verified correct via property testing against 500 random sequences; added a bound on max_mismatches to prevent degenerate output near the random-match noise floor.
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