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mtariqi/README.md

🧬 Building AI-driven Computational Methods for Precision Medicine


πŸ‘¨β€πŸ”¬ About Me

I am a Senior Research Scientist specializing in Computational Biology, Bioinformatics, Artificial Intelligence, and Precision Medicine.

My research combines genomics, transcriptomics, multi-omics integration, machine learning, and large language models (LLMs) to transform complex biological data into actionable insights for biomarker discovery, therapeutic target identification, and AI-assisted drug discovery.

Currently, I work as a Bioinformatician at the University of Arkansas for Medical Sciences (UAMS), where I develop scalable NGS pipelines, AI-driven computational workflows, and reproducible bioinformatics systems using TCGA and CPTAC datasets to advance cancer genomics research.

My long-term vision is to build intelligent computational systems that bridge biology and artificial intelligence to accelerate scientific discovery and improve patient outcomes.


πŸ”¬ Research Interests

🧬 Computational Biology

🧬 Cancer Genomics

🧬 Precision Oncology

🧬 Bioinformatics

🧬 Multi-Omics Integration

πŸ’Š Drug Discovery

πŸ€– Artificial Intelligence

🧠 Machine Learning & Deep Learning

πŸ“š Large Language Models (LLMs)

⚑ Agentic AI

☁️ Scientific Computing


Scientific Contributions

Healthcare Data Engineering
β”‚
β”œβ”€β”€ NIH Clinical Trials Lakehouse
β”œβ”€β”€ CDC Healthcare Streaming ETL
β”‚

Bioinformatics
β”‚
β”œβ”€β”€ TCGA CPTAC Kafka
β”œβ”€β”€ Synthetic Variant Calling
β”œβ”€β”€ USAG1 Validation
β”‚

Artificial Intelligence
β”‚
β”œβ”€β”€ Genomic Foundation Models
β”‚

Research
β”‚
β”œβ”€β”€ TNBC AI Drug Discovery
β”œβ”€β”€ RTK NRTK Project

βœ” Hybrid-CORE

AI framework for rational drug combination discovery.

βœ” RTK/NRTK

Discovery of compensatory kinase networks using TCGA.

βœ” Biomedical Agentic RAG

LLM-powered biomedical evidence synthesis.

βœ” Foundation Models

Transformer models for genomic sequences.

βš™οΈ Technology Stack

Programming

Artificial Intelligence

Bioinformatics

Cloud & Infrastructure


πŸš€ Featured Research Projects

πŸ₯ NIH Clinical Trials Lakehouse

Production healthcare data engineering platform

GitHub

https://github.com/mtariqi/nih-clinical-trials-lakehouse-pipeline

🌍 CDC Healthcare Streaming ETL

Healthcare streaming analytics pipeline

https://github.com/mtariqi/cdc-healthcare-streaming-etl-pipeline

🎯 TNBC Drug Discovery Pipeline

AI-driven precision oncology

https://github.com/mtariqi/tnbc-drug-discovery-pipeline

🧬 TCGA-CPTAC Kafka Platform

Large-scale cancer multi-omics

https://github.com/mtariqi/tcga-cptac-kafka-bioinformatics

πŸ§ͺ Synthetic Variant Calling Benchmark

Next-generation sequencing benchmarking

https://github.com/mtariqi/synthetic-variant-calling-benchmark

πŸ€– Genomic Foundation Models

Transformer models for genomics

https://github.com/mtariqi/genomic-foundation-models

🦷 USAG1 Validation

Computational target validation

https://github.com/mtariqi/USAG1-Validation


πŸ“Š GitHub Statistics


πŸ“ˆ Current Research Focus

  • 🧬 AI for Precision Oncology
  • πŸ’Š Computational Drug Discovery
  • 🧠 Foundation Models for Genomics
  • πŸ“š Biomedical Large Language Models
  • ⚑ Agentic AI for Scientific Discovery
  • πŸ”¬ Cancer Multi-Omics
  • ☁️ Scalable Scientific Computing

Education

MS Bioinformatics

MSc Molecular Biology

MS Biotechnology

BSc Biotechnology and Genetic Engineering

Certifications

Johns Hopkins University

Health Informatics

University of Toronto

Business Analytics

Project Management

Advanced Data Science

Cloud Computing

🌱 Currently Learning

  • Agentic AI
  • Foundation Models
  • Multi-agent Systems
  • Biomedical LLMs
  • Causal AI

🀝 Let's Collaborate

I welcome collaborations in

  • Computational Biology
  • Bioinformatics
  • Precision Medicine
  • Cancer Genomics
  • Artificial Intelligence
  • Drug Discovery
  • Machine Learning
  • Healthcare AI
  • Scientific Software Development

Contact

LinkedIn

https://www.linkedin.com/in/mdtariqulscired

GitHub

https://github.com/mtariqi

Email

[email protected]

Future Roadmap

Healthcare Data Engineering β”‚ β–Ό Public Health Analytics β”‚ β–Ό Cancer Multi-omics β”‚ β–Ό AI Drug Discovery β”‚ β–Ό Foundation Models β”‚ β–Ό Agentic AI for Precision Medicine

"Transforming Biological Data into Intelligent Therapeutic Discovery"

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    Config files for my GitHub profile.

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