Parse different glycan structure text nomenclature into
glyrepr::glycan_structure.
Currently, the following formats are supported: IUPAC-extended, IUPAC-condensed, IUPAC-short, WURCS, GlycoCT, StrucGP-style, pGlyco-style.
You can install the latest release of glyparse from CRAN:
pak::pkg_install("glyparse")Or from r-universe:
pak::repo_add(glycoverse = "https://glycoverse.r-universe.dev")
pak::pkg_install("glyparse")Or install the latest GitHub release:
pak::pkg_install("glycoverse/glyparse@*release")Or install the development version from GitHub:
pak::pkg_install("glycoverse/glyparse")While glyrepr natively supports parsing IUPAC-condensed format through
as_glycan_structure(), the glycan community has developed numerous
other nomenclature formats that remain widely adopted in different
contexts. glyparse serves as a comprehensive extension to glyrepr,
providing robust parsing capabilities for these diverse formats. The
package can be utilized directly by researchers to parse glycan
structure text strings, or integrated with other packages such as
glyread to seamlessly handle structure parsing when processing results
from glycan and glycopeptide analysis software.
library(glyparse)# Parse a StrucGP-style structure string
parse_strucgp_struc("A2B2C1D1E2F1fedD1E2edcbB5ba")
#> <glycan_structure[1]>
#> [1] Hex(??-?)HexNAc(??-?)Hex(??-?)[HexNAc(??-?)Hex(??-?)]Hex(??-?)HexNAc(??-?)[dHex(??-?)]HexNAc(??-
#> # Unique structures: 1# Parse a pGlyco-style structure string
parse_pglyco_struc("(N(F)(N(H(H(N))(H(N(H))))))")
#> <glycan_structure[1]>
#> [1] Hex(??-?)HexNAc(??-?)Hex(??-?)[HexNAc(??-?)Hex(??-?)]Hex(??-?)HexNAc(??-?)[dHex(??-?)]HexNAc(??-
#> # Unique structures: 1# Parse a condensed IUPAC structure string
parse_iupac_condensed("Gal(b1-3)GlcNAc(b1-4)Glc(a1-")
#> <glycan_structure[1]>
#> [1] Gal(b1-3)GlcNAc(b1-4)Glc(a1-
#> # Unique structures: 1# Parse a WURCS structure string
parse_wurcs("WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1")
#> <glycan_structure[1]>
#> [1] Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc(b1-
#> # Unique structures: 1