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andraderenew/README.md

Rene Andrade Rey

Physician & Neuroimaging Researcher

I build reproducible neuroimaging workflows across structural MRI, task and resting-state fMRI, diffusion MRI, MEG, EEG, and PET.

My work emphasizes transparent processing, quality control, cross-software validation, open science, and technically documented analysis pipelines.

Featured completed projects

Modality Project Main tools Repository Zenodo
Diffusion MRI Preprocessing, DTI, CSD, tractography, SIFT, and quantitative QC MRtrix3, FSL Eddy View project 10.5281/zenodo.21629553
Task fMRI Auditory first-level analysis and cross-software replication SPM25, FSL FEAT View project 10.5281/zenodo.17715105
Resting-state fMRI Functional connectomics, graph analysis, hubs, and BRAPH-ready exports Nilearn, NetworkX, FSL, BRAPH-ready outputs View project 10.5281/zenodo.17715117
MEG Median-nerve ERFs, dSPM source reconstruction, and time-frequency analysis Brainstorm, dSPM, Morlet wavelets View project 10.5281/zenodo.17715112
EEG Group-level ERPs, time-frequency power, and exact paired cluster-permutation statistics EEGLAB, FieldTrip, MATLAB View project 10.5281/zenodo.21826210
Structural MRI Tissue segmentation, quality control, global volumes, and VBM preparation CAT26, SPM25, MATLAB View project 10.5281/zenodo.21629555
Structural MRI Cortical reconstruction, morphometry, regional statistics, and Freeview QC FreeSurfer 7.4.1 View project 10.5281/zenodo.21629557
PET Dynamic FDG PET, SUVR, PETPVE12 PVC, regional analysis, and PSF sensitivity FSL MCFLIRT, SPM12, PETPVE12 View project Pending Zenodo integration repair

Completed workflow highlights

Diffusion MRI — MRtrix3 and FSL

Reproducible single-subject diffusion MRI workflow using public MPI-LEMON data.

  • MP-PCA denoising and Gibbs-ringing correction
  • Motion, eddy-current, and outlier correction with FSL Eddy
  • Diffusion tensor fitting with FA, MD, AD, and RD maps
  • Single-shell constrained spherical deconvolution
  • Probabilistic iFOD2 whole-brain tractography
  • SIFT filtering and track-density imaging
  • Automated quality-control figures and quantitative summaries

Task fMRI — SPM25 and FSL FEAT

Single-subject analysis of the classic SPM Auditory dataset, implemented independently in SPM25 and FSL FEAT.

  • Contrast: Listening > Rest
  • Motion quality control
  • First-level GLM
  • Statistical maps and cluster tables
  • Cross-software comparison

Resting-state fMRI — Functional connectomics and graph analysis

Ten-subject ADHD-200 preprocessed resting-state workflow using the Schaefer-100 atlas.

  • Nuisance regression and temporal filtering
  • Subject-level Pearson connectivity matrices
  • Fisher-z group averaging
  • Minimum-spanning-tree plus 15% density graph construction
  • NetworkX graph metrics, communities, hubs, and small-world analysis
  • BRAPH-ready matrix and label exports

MEG — Brainstorm median-nerve analysis

Reproduction of the Brainstorm median-nerve workflow.

  • Sensor-level event-related fields
  • Early somatosensory topography at approximately 20 ms
  • Minimum-norm dSPM source reconstruction
  • Morlet time-frequency analysis from 4 to 80 Hz

EEG — STERN ERPs and time-frequency analysis

Completed group-level analysis of the EEGLAB STERN tutorial study using EEGLAB and FieldTrip.

  • 13 participants, 39 condition-specific datasets, 9,678 epochs, and 20,697 events
  • ERP and 4–30 Hz time-frequency analysis across 69 common scalp channels
  • Primary event-matched contrast: Memorize − Ignore
  • Positive ERP cluster from 440–552 ms and negative ERP cluster from 632–760 ms
  • Negative time-frequency cluster spanning 4–26 Hz and 0.00–1.40 s
  • Exact paired cluster tests using all 8,192 possible within-subject permutations
  • Subject-level and leave-one-subject-out robustness checks

Primary EEG time-frequency contrast

Structural MRI — CAT26 and SPM25

Single-subject T1-weighted structural MRI workflow.

  • Bias-field correction
  • Grey matter, white matter, and CSF segmentation
  • Spatial normalization and modulation
  • CAT quality-control assessment
  • Global tissue-volume extraction
  • Preparation of smoothed grey matter for VBM

Structural MRI — FreeSurfer

Single-subject cortical reconstruction and morphometry using OpenNeuro ds000114.

  • Complete recon-all cortical reconstruction
  • Parallel execution with -openmp 8
  • Subcortical and global volumetric statistics
  • Cortical thickness, area, and volume by Desikan–Killiany region
  • Coronal, sagittal, and axial Freeview quality-control figures

PET — FDG SUVR and PETPVE12 partial-volume correction

Completed, quality-controlled single-subject research portfolio demonstration using public OpenNeuro dataset ds002898, subject sub-01.

  • 225 dynamic FDG PET frames selected from approximately 30 to 90 minutes
  • 2.8 mm isotropic resampling and FSL MCFLIRT motion correction
  • Static PET construction, SPM12 tissue segmentation, and PET-to-T1 coregistration
  • PETPVE12 Müller–Gärtner partial-volume correction at nominal 4, 5, 6, and 8 mm PSF values
  • Bilateral cerebellar-cortex SUVR and Desikan–Killiany regional summaries
  • 84 predefined primary grey-matter ROIs; 81 form the post hoc QA robustness subset (GM support >=20 voxels)
  • Robust cerebellar-normalized PVC-SUVR PSF CV: median 1.437%, maximum 6.037%
  • Robust pre-normalization PVC-activity PSF CV: median 3.029%, maximum 8.587%
  • Final workflow validation passed
  • Research portfolio demonstration only; not clinical or diagnostic software

Current methodological comparison

Modality Project Status Repository
Structural MRI CAT26/SPM25 versus FreeSurfer on the same OpenNeuro ds000114 T1-weighted image Current descriptive cross-method comparison; no population inference or completed region-by-region agreement claim View project

Archived historical scaffolds that have been superseded or discontinued are intentionally omitted from the active portfolio presentation.

Technical toolkit

Neuroimaging

SPM · FSL/FEAT · FreeSurfer · CAT26 · Brainstorm · MRtrix3 · PETPVE12 · BRAPH · EEGLAB · FieldTrip

Programming and reproducibility

Python · MATLAB · Bash · Git · BIDS · statistical modelling · scientific visualization

Research interests

  • Structural and functional brain connectivity
  • Diffusion MRI and tractography
  • Reproducible neuroimaging
  • Multimodal integration
  • Neuroimaging quality control
  • Source imaging
  • Graph-theoretical analysis
  • Clinical and translational neuroscience

Research profiles


Raw neuroimaging data are generally excluded from the repositories. Each completed project documents its data source, processing decisions, software environment, outputs, and limitations.

Popular repositories Loading

  1. tvb-documentation tvb-documentation Public

    Forked from the-virtual-brain/tvb-documentation

    TVB documentation: RST and iPython notebooks

    Jupyter Notebook 1

  2. NeuroFusion-Explorer NeuroFusion-Explorer Public

    Forked from NEUROFUSIONInc/NeuroFusion-Explorer

    Scripts we use for collecting and analyzing brain and behavior data on NeuroFusion

    Jupyter Notebook 1

  3. portable_EEG portable_EEG Public archive

    This repository contains some of the codes I have done to compute ERP based on portable eeg like Muse and Neurosity

    Python 1

  4. eeg_erps-tf_eeglab-fieldtrip_sternberg eeg_erps-tf_eeglab-fieldtrip_sternberg Public

    Group-level EEG ERP and time-frequency analysis of the STERN dataset with EEGLAB, FieldTrip, and exact paired cluster permutations.

    MATLAB 1

  5. meg_erfs-sources_brainstorm_median-nerve meg_erfs-sources_brainstorm_median-nerve Public

    Brainstorm median-nerve MEG workflow with ERFs, dSPM source reconstruction, and Morlet time-frequency analysis.

    1

  6. DeepLearningTutorials DeepLearningTutorials Public

    Forked from lisa-lab/DeepLearningTutorials

    Deep Learning Tutorial notes and code. See the wiki for more info.

    Python