9base status: Historical Downstream. Historical Downstream of thekaplanlab/ConVarT_Web. ConVarT is Kaplan Lab scientific software; historical 9base development added configuration, search/schema, development setup and UI changes. This downstream is no longer actively maintained. The inherited scientific overview remains below.
Documentation reconstructed from repository history on 8 October 2026. See 9base provenance and patch notes.
The conserved clinical variation visualization tool (ConVarT) is an online visualization resource developed by the Kaplan Lab, with the goal of displaying the evolutionary conservation of amino acid substitutions associated with diseases from ClinVar and gnomAD databases, and allowing easy access to collections of conserved genes and conserved variants associated with human diseases for the model organism research community.
All genes consisting of all types of amino acid substitutions from ClinVar and gnomAD databases have been extracted, and a series of multiple sequence alignments of ortholog genes between human, chimp, macaca, zebrafish, mouse, rat, Xenopus, Drosophila, and C. elegans have been performed, with integration of human disease causing amino acid into corresponding positions. The data visualization tool is freely available for the benefit of the scientific community.
Details coming soon